Precision Medicine Clinic: Molecular Tumor Board
Precision Medicine Clinic: Molecular Tumor Board is a case-based series designed to help clinicians optimize molecular testing for their patients. The Editors of The Oncologist encourage institutions to share their findings and experiences to help improve the precision of genomic oncology and fulfill its promise of improved outcomes for patients. This collection highlights a diverse set of patients exhibiting a range of tumor types and mutations. We hope you find the clinical outcomes beneficial in your practice.
Understanding the Precision in “Precision Medicine”
Bruce A. Chabner
The Oncologist 2016; 21:1029-1030; first published on August 26, 2016;doi:10.1634/theoncologist.2016-0278
Search by Type:
ALK | BRCA | EGFR | ERBB2 | ESR1 | IDH | KRAS | MET | POLE | SMAD4 | SMARCB1 | TMB | Immunotherapy | Germline mutations/Hereditary syndromes
ALK
Peng Zhao, Ling Peng, Wei Wu, Yi Zheng, Weiqin Jiang, Hangyu Zhang, Zhou Tong, Lulu Liu, Ruobing Ma, Liping Wang, Ming Yao, Kai Wang, Weijia Fang, Liming Wu
The Oncologist first published on January 24, 2019; doi:10.1634/theoncologist.2018-0439
The Oncologist first published on January 24, 2019; doi:10.1634/theoncologist.2018-0439
Fernando Vargas-Madueno, Edwin Gould, Raul Valor, Nhu Ngo, Linsheng Zhang, Miguel A. Villalona-Calero
The Oncologist first published on May 8, 2018; doi:10.1634/theoncologist.2018-0014
The Oncologist first published on May 8, 2018; doi:10.1634/theoncologist.2018-0014
Victoria E. Wang, Lauren Young, Siraj Ali, Vincent A. Miller, Anatoly Urisman, John Wolfe, Trever G. Bivona, Bertil Damato, Shannon Fogh, Emily K. Bergsland
The Oncologist 2017; 22:768-773; first published on May 15, 2017; doi:10.1634/theoncologist.2017-0054
The Oncologist 2017; 22:768-773; first published on May 15, 2017; doi:10.1634/theoncologist.2017-0054
Andrea Z. Lai, Alexa B. Schrock, Rachel L. Erlich, Jeffrey S. Ross, Vincent A. Miller, Evgeny Yakirevich, Siraj M. Ali, Fadi Braiteh
The Oncologist 2017; 22:774-779; first published on May 15, 2017; doi:10.1634/theoncologist.2016-0376
The Oncologist 2017; 22:774-779; first published on May 15, 2017; doi:10.1634/theoncologist.2016-0376
BRCA
Daniel R. Principe, Suneel D. Kamath, Hidayatullah G. Munshi, Nisha A. Mohindra
The Oncologist first published on November 1, 2019; doi:10.1634/theoncologist.2019-0393
The Oncologist first published on November 1, 2019; doi:10.1634/theoncologist.2019-0393
Huat C. Lim, Meagan Montesion, Thomas Botton, Eric A. Collisson, Sarah E. Umetsu, Spencer C. Behr, John D. Gordan, Phil J. Stephens, Robin K. Kelley
The Oncologist first published on April 5, 2018; doi:10.1634/theoncologist.2017-0645
The Oncologist first published on April 5, 2018; doi:10.1634/theoncologist.2017-0645
Don S. Dizon, Dora Dias-Santagata, Amy Bregar, Laura Sullivan, Jennifer Filipi, Elizabeth DiTavi, Lucy Miller, Leif Ellisen, Michael Birrer, Marcela DelCarmen
The Oncologist first published on February 22, 2018; doi:10.1634/theoncologist.2017-0526
The Oncologist first published on February 22, 2018; doi:10.1634/theoncologist.2017-0526
EGFR
Yong Li, Hai‐Bo Zhang, Xian Chen, Xiaobing Yang, Yongsong Ye, Tanios Bekaii‐Saab, Yaojie Zheng, Yihong Zhang
The Oncologist first published on October 22, 2019; doi:10.1634/theoncologist.2019-0405
The Oncologist first published on October 22, 2019; doi:10.1634/theoncologist.2019-0405
Yan Guan, Zhanshuai Song, Yan Li, Honglin Guo, Junping Shi, Xuemei Zhang, Ming Yao
The Oncologist first published on May 7, 2019; doi:10.1634/theoncologist.2018-0732
The Oncologist first published on May 7, 2019; doi:10.1634/theoncologist.2018-0732
Kohei Otsubo, Kazuko Sakai, Masafumi Takeshita, Daijiro Harada, Koichi Azuma, Keiichi Ota, Hiroaki Akamatsu, Koichi Goto, Atsushi Horiike, Takayasu Kurata, Noriaki Nakagaki, Kaname Nosaki, Eiji Iwama, Yoichi Nakanishi, Kazuto Nishio, Isamu Okamoto
The Oncologist first published on April 25, 2019; doi:10.1634/theoncologist.2019-0101
The Oncologist first published on April 25, 2019; doi:10.1634/theoncologist.2019-0101
Santiago Cabezas-Camarero, Virginia de la Orden García, Vanesa GarcÍa-Barberán, Beatriz Mediero-Valeros, Ahmad Issa Subhi-Issa, Patricia Llovet García, Inmaculada Bando-Polaino, Salomé Merino Menéndez, Pedro Pérez-Segura, Eduardo Díaz-Rubio
The Oncologist first published on January 2, 2019; doi:10.1634/theoncologist.2018-0387
The Oncologist first published on January 2, 2019; doi:10.1634/theoncologist.2018-0387
ERBB2
Hiromasa Yamamoto, Shinichi Toyooka, Takashi Ninomiya, Shigemi Matsumoto, Masashi Kanai, Shuta Tomida, Katsuyuki Kiura, Manabu Muto, Ken Suzawa, Patrice Desmeules, Mark G. Kris, Bob T. Li, Marc Ladanyi
The Oncologist 2018; 23:150-154; first published on November 16, 2017; doi:10.1634/theoncologist.2017-0345
The Oncologist 2018; 23:150-154; first published on November 16, 2017; doi:10.1634/theoncologist.2017-0345
ESR1
Aditya Bardia, John A. Iafrate, Tilak Sundaresan, Jerry Younger, Valentina Nardi
The Oncologist 2016; 21:1035-1040; first published on August 22, 2016; doi:10.1634/theoncologist.2016-0240
The Oncologist 2016; 21:1035-1040; first published on August 22, 2016; doi:10.1634/theoncologist.2016-0240
IDH
Suneel Deepak Kamath, Xiaoqi Lin, Aparna Kalyan
The Oncologist first published on October 23, 2018; doi:10.1634/theoncologist.2018-0210
The Oncologist first published on October 23, 2018; doi:10.1634/theoncologist.2018-0210
KRAS
Bijun Lian, Wenhui Zhang, Tiegong Wang, Qingsong Yang, Zepeng Jia, Huan Chen, Lei Wang, Jing Xu, Wei Wang, Kai Cao, Xu Gao, Yinghao Sun, Chengwei Shao, Zhiyong Liu, Jing Li
The Oncologist first published on September 6, 2018; doi:10.1634/theoncologist.2018-0295
The Oncologist first published on September 6, 2018; doi:10.1634/theoncologist.2018-0295
MET
Lisa Pei Chu, Debra Franck, Christine A. Parachoniak, Jeffrey P. Gregg, Michael G. Moore, D. Gregory Farwell, Shyam Rao, Andreas M. Heilmann, Rachel L. Erlich, Jeffrey S. Ross, Vincent A. Miller, Siraj Ali, Jonathan W. Riess
The Oncologist first published on August 7, 2019; doi:10.1634/theoncologist.2019-0230
The Oncologist first published on August 7, 2019; doi:10.1634/theoncologist.2019-0230
POLE
DNA Polymerase ϵ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity
Enrico Castellucci, Tianfang He, D. Yitzchak Goldstein, Balazs Halmos, Jennifer ChuyThe Oncologist 2017; 22:497-502; first published on May 2, 2017; doi:10.1634/theoncologist.2017-0034
SMAD4
Nicky D'Haene, Marie Le Mercier, Isabelle Salmon, Zita Mekinda, Myriam Remmelink, Thierry Berghmans
The Oncologist first published on November 9, 2018; doi:10.1634/theoncologist.2018-0016
The Oncologist first published on November 9, 2018; doi:10.1634/theoncologist.2018-0016
SMARCB1
Theodoros Karantanos, Lisa Rooper, Youme Kang, Cheng Ting Lin, Pawla Wenga, Sarah Sagorsky, Josh Lauring, Hyunseok Kang
The Oncologist first published on October 8, 2018; doi:10.1634/theoncologist.2018-0279
The Oncologist first published on October 8, 2018; doi:10.1634/theoncologist.2018-0279
TMB
Munveer S. Bhangoo, Peter Boasberg, Pareen Mehta, Julia A. Elvin, Siraj M. Ali, Winnie Wu, Samuel J. Klempner
The Oncologist first published on January 31, 2018; doi:10.1634/theoncologist.2017-0342
The Oncologist first published on January 31, 2018; doi:10.1634/theoncologist.2017-0342
Andrew Sharabi, Sangwoo Shawn Kim, Shumei Kato, Philip D. Sanders, Sandip Pravin Patel, Parag Sanghvi, Elizabeth Weihe, Razelle Kurzrock
The Oncologist 2017; 22:631-637; first published on May 26, 2017; doi:10.1634/theoncologist.2016-0517
The Oncologist 2017; 22:631-637; first published on May 26, 2017; doi:10.1634/theoncologist.2016-0517
Immunotherapy
Charlotte Manogue, Patrick Cotogno, Elisa Ledet, Brian Lewis, Alexander W. Wyatt, Oliver Sartor
The Oncologist first published on December 12, 2018; doi:10.1634/theoncologist.2018-0546
The Oncologist first published on December 12, 2018; doi:10.1634/theoncologist.2018-0546
Pradnya D. Patil, Anthony P. Fernandez, Vamsidhar Velcheti, Ahmad Tarhini, Pauline Funchain, Brian Rini, Mohamad Khasawneh, Nathan A. Pennell
The Oncologist first published on October 24, 2018; doi:10.1634/theoncologist.2018-0434
The Oncologist first published on October 24, 2018; doi:10.1634/theoncologist.2018-0434
Musa AlHarbi, Nahla Ali Mobark, Latifa AlMubarak, Rasha Aljelaify, Mariam AlSaeed, Amal Almutairi, Fatmah Alqubaishi, M. Emarat Hussain, Ali Abdullah O. Balbaid, Amal Said Marie, Lamia AlSubaie, Saeed AlShieban, Nada alTassan, Shakti H. Ramkissoon, Malak Abedalthagafi
The Oncologist first published on August 13, 2018; doi:10.1634/theoncologist.2018-0163
The Oncologist first published on August 13, 2018; doi:10.1634/theoncologist.2018-0163
Revathi Kollipara, Bryan Schneider, Milan Radovich, Sunil Babu, Patrick J. Kiel
The Oncologist 2017; 22:1149-1151; first published on August 4, 2017; doi:10.1634/theoncologist.2017-0096
The Oncologist 2017; 22:1149-1151; first published on August 4, 2017; doi:10.1634/theoncologist.2017-0096
Shyam A. Patel, Teri A. Longacre, Uri Ladabaum, Alexandra Lebensohn, Albert Y. Lin, Sigurdis Haraldsdottir
The Oncologist first published on August 2, 2018; doi:10.1634/theoncologist.2018-0108
The Oncologist first published on August 2, 2018; doi:10.1634/theoncologist.2018-0108
Germline mutations/Hereditary syndromes
Arthur Winer, Pooja Ghatalia, Nicole Bubes, Fern Anari, Asya Varshavsky, Vineela Kasireddy, Yang Liu, Wafik S. El-Deiry
The Oncologist first published on August 23, 2019; doi:10.1634/theoncologist.2018-0686
The Oncologist first published on August 23, 2019; doi:10.1634/theoncologist.2018-0686
Claudia Maletzki, Maja Höhns, Ingrid Bauer, Friedrich Prall, Christian Junghanss, Larissa Henze
The Oncologist first published on January 25, 2019; doi:10.1634/theoncologist.2018-0614
The Oncologist first published on January 25, 2019; doi:10.1634/theoncologist.2018-0614
Steven Sorscher
The Oncologist first published on June 4, 2018; doi:10.1634/theoncologist.2017-0681
The Oncologist first published on June 4, 2018; doi:10.1634/theoncologist.2017-0681
Nicole Casasanta, Elizabeth Stark, Allison McHenry, Tara Biagi, Rebecca Kaltman
The Oncologist first published on February 14, 2018; doi:10.1634/theoncologist.2017-0372
The Oncologist first published on February 14, 2018; doi:10.1634/theoncologist.2017-0372
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