Precision Medicine Clinic: Molecular Tumor Board

Precision Medicine Clinic: Molecular Tumor Board is a case-based series designed to help clinicians optimize molecular testing for their patients. The Editors of The Oncologist encourage institutions to share their findings and experiences to help improve the precision of genomic oncology and fulfill its promise of improved outcomes for patients. This collection highlights a diverse set of patients exhibiting a range of tumor types and mutations. We hope you find the clinical outcomes beneficial in your practice.

Understanding the Precision in “Precision Medicine”

Bruce A. Chabner
The Oncologist 2016; 21:1029-1030; first published on August 26, 2016;doi:10.1634/theoncologist.2016-0278


Search by Type:

ALK | BRCA | EGFR | ERBB2 | ESR1 | IDH | KRAS | MET | POLE | SMAD4 | SMARCB1 | TMB | Immunotherapy | Germline mutations/Hereditary syndromes

 

ALK


Peng Zhao, Ling Peng, Wei Wu, Yi Zheng, Weiqin Jiang, Hangyu Zhang, Zhou Tong, Lulu Liu, Ruobing Ma, Liping Wang, Ming Yao, Kai Wang, Weijia Fang, Liming Wu
The Oncologist first published on January 24, 2019; doi:10.1634/theoncologist.2018-0439
Fernando Vargas-Madueno, Edwin Gould, Raul Valor, Nhu Ngo, Linsheng Zhang, Miguel A. Villalona-Calero
The Oncologist first published on May 8, 2018; doi:10.1634/theoncologist.2018-0014
Victoria E. Wang, Lauren Young, Siraj Ali, Vincent A. Miller, Anatoly Urisman, John Wolfe, Trever G. Bivona, Bertil Damato, Shannon Fogh, Emily K. Bergsland
The Oncologist 2017; 22:768-773; first published on May 15, 2017; doi:10.1634/theoncologist.2017-0054
Andrea Z. Lai, Alexa B. Schrock, Rachel L. Erlich, Jeffrey S. Ross, Vincent A. Miller, Evgeny Yakirevich, Siraj M. Ali, Fadi Braiteh
The Oncologist 2017; 22:774-779; first published on May 15, 2017; doi:10.1634/theoncologist.2016-0376


BRCA


Daniel R. Principe, Suneel D. Kamath, Hidayatullah G. Munshi, Nisha A. Mohindra
The Oncologist first published on November 1, 2019; doi:10.1634/theoncologist.2019-0393
Huat C. Lim, Meagan Montesion, Thomas Botton, Eric A. Collisson, Sarah E. Umetsu, Spencer C. Behr, John D. Gordan, Phil J. Stephens, Robin K. Kelley
The Oncologist first published on April 5, 2018; doi:10.1634/theoncologist.2017-0645
Don S. Dizon, Dora Dias-Santagata, Amy Bregar, Laura Sullivan, Jennifer Filipi, Elizabeth DiTavi, Lucy Miller, Leif Ellisen, Michael Birrer, Marcela DelCarmen
The Oncologist first published on February 22, 2018; doi:10.1634/theoncologist.2017-0526


EGFR


Yong Li, Hai‐Bo Zhang, Xian Chen, Xiaobing Yang, Yongsong Ye, Tanios Bekaii‐Saab, Yaojie Zheng, Yihong Zhang
The Oncologist first published on October 22, 2019; doi:10.1634/theoncologist.2019-0405
Yan Guan, Zhanshuai Song, Yan Li, Honglin Guo, Junping Shi, Xuemei Zhang, Ming Yao
The Oncologist first published on May 7, 2019; doi:10.1634/theoncologist.2018-0732
Kohei Otsubo, Kazuko Sakai, Masafumi Takeshita, Daijiro Harada, Koichi Azuma, Keiichi Ota, Hiroaki Akamatsu, Koichi Goto, Atsushi Horiike, Takayasu Kurata, Noriaki Nakagaki, Kaname Nosaki, Eiji Iwama, Yoichi Nakanishi, Kazuto Nishio, Isamu Okamoto
The Oncologist first published on April 25, 2019; doi:10.1634/theoncologist.2019-0101
Santiago Cabezas-Camarero, Virginia de la Orden García, Vanesa GarcÍa-Barberán, Beatriz Mediero-Valeros, Ahmad Issa Subhi-Issa, Patricia Llovet García, Inmaculada Bando-Polaino, Salomé Merino Menéndez, Pedro Pérez-Segura, Eduardo Díaz-Rubio
The Oncologist first published on January 2, 2019; doi:10.1634/theoncologist.2018-0387


ERBB2


Hiromasa Yamamoto, Shinichi Toyooka, Takashi Ninomiya, Shigemi Matsumoto, Masashi Kanai, Shuta Tomida, Katsuyuki Kiura, Manabu Muto, Ken Suzawa, Patrice Desmeules, Mark G. Kris, Bob T. Li, Marc Ladanyi
The Oncologist 2018; 23:150-154; first published on November 16, 2017; doi:10.1634/theoncologist.2017-0345


ESR1


Aditya Bardia, John A. Iafrate, Tilak Sundaresan, Jerry Younger, Valentina Nardi
The Oncologist 2016; 21:1035-1040; first published on August 22, 2016; doi:10.1634/theoncologist.2016-0240

 

IDH


Suneel Deepak Kamath, Xiaoqi Lin, Aparna Kalyan
The Oncologist first published on October 23, 2018; doi:10.1634/theoncologist.2018-0210

 

KRAS


Bijun Lian, Wenhui Zhang, Tiegong Wang, Qingsong Yang, Zepeng Jia, Huan Chen, Lei Wang, Jing Xu, Wei Wang, Kai Cao, Xu Gao, Yinghao Sun, Chengwei Shao, Zhiyong Liu, Jing Li
The Oncologist first published on September 6, 2018; doi:10.1634/theoncologist.2018-0295

 

MET


Lisa Pei Chu, Debra Franck, Christine A. Parachoniak, Jeffrey P. Gregg, Michael G. Moore, D. Gregory Farwell, Shyam Rao, Andreas M. Heilmann, Rachel L. Erlich, Jeffrey S. Ross, Vincent A. Miller, Siraj Ali, Jonathan W. Riess
The Oncologist first published on August 7, 2019; doi:10.1634/theoncologist.2019-0230

 

POLE


Enrico Castellucci, Tianfang He, D. Yitzchak Goldstein, Balazs Halmos, Jennifer Chuy
The Oncologist 2017; 22:497-502; first published on May 2, 2017; doi:10.1634/theoncologist.2017-0034

 

SMAD4


Nicky D'Haene, Marie Le Mercier, Isabelle Salmon, Zita Mekinda, Myriam Remmelink, Thierry Berghmans
The Oncologist first published on November 9, 2018; doi:10.1634/theoncologist.2018-0016

 

SMARCB1


Theodoros Karantanos, Lisa Rooper, Youme Kang, Cheng Ting Lin, Pawla Wenga, Sarah Sagorsky, Josh Lauring, Hyunseok Kang
The Oncologist first published on October 8, 2018; doi:10.1634/theoncologist.2018-0279

 

TMB


Munveer S. Bhangoo, Peter Boasberg, Pareen Mehta, Julia A. Elvin, Siraj M. Ali, Winnie Wu, Samuel J. Klempner
The Oncologist first published on January 31, 2018; doi:10.1634/theoncologist.2017-0342
Andrew Sharabi, Sangwoo Shawn Kim, Shumei Kato, Philip D. Sanders, Sandip Pravin Patel, Parag Sanghvi, Elizabeth Weihe, Razelle Kurzrock
The Oncologist 2017; 22:631-637; first published on May 26, 2017; doi:10.1634/theoncologist.2016-0517


Immunotherapy


Charlotte Manogue, Patrick Cotogno, Elisa Ledet, Brian Lewis, Alexander W. Wyatt, Oliver Sartor
The Oncologist first published on December 12, 2018; doi:10.1634/theoncologist.2018-0546
Pradnya D. Patil, Anthony P. Fernandez, Vamsidhar Velcheti, Ahmad Tarhini, Pauline Funchain, Brian Rini, Mohamad Khasawneh, Nathan A. Pennell
The Oncologist first published on October 24, 2018; doi:10.1634/theoncologist.2018-0434
Musa AlHarbi, Nahla Ali Mobark, Latifa AlMubarak, Rasha Aljelaify, Mariam AlSaeed, Amal Almutairi, Fatmah Alqubaishi, M. Emarat Hussain, Ali Abdullah O. Balbaid, Amal Said Marie, Lamia AlSubaie, Saeed AlShieban, Nada alTassan, Shakti H. Ramkissoon, Malak Abedalthagafi
The Oncologist first published on August 13, 2018; doi:10.1634/theoncologist.2018-0163
Revathi Kollipara, Bryan Schneider, Milan Radovich, Sunil Babu, Patrick J. Kiel
The Oncologist 2017; 22:1149-1151; first published on August 4, 2017; doi:10.1634/theoncologist.2017-0096
Shyam A. Patel, Teri A. Longacre, Uri Ladabaum, Alexandra Lebensohn, Albert Y. Lin, Sigurdis Haraldsdottir
The Oncologist first published on August 2, 2018; doi:10.1634/theoncologist.2018-0108


Germline mutations/Hereditary syndromes


Arthur Winer, Pooja Ghatalia, Nicole Bubes, Fern Anari, Asya Varshavsky, Vineela Kasireddy, Yang Liu, Wafik S. El-Deiry
The Oncologist first published on August 23, 2019; doi:10.1634/theoncologist.2018-0686
Claudia Maletzki, Maja Höhns, Ingrid Bauer, Friedrich Prall, Christian Junghanss, Larissa Henze
The Oncologist first published on January 25, 2019; doi:10.1634/theoncologist.2018-0614
Steven Sorscher
The Oncologist first published on June 4, 2018; doi:10.1634/theoncologist.2017-0681
Nicole Casasanta, Elizabeth Stark, Allison McHenry, Tara Biagi, Rebecca Kaltman
The Oncologist first published on February 14, 2018; doi:10.1634/theoncologist.2017-0372


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