European Perspectives


Unus pro Omnibus, Omnes pro Uno (One for All, All for One)

H.M. Pinedo

The Oncologist first published on June 23, 2020; doi: 10.1634/theoncologist.2020-0532


Personalized Risk–Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID ‐19 Outbreak

Giulia Viale, Luca Licata, Lorenzo Sica, Stefania Zambelli, Patrizia Zucchinelli, Alessia Rognone, Daniela Aldrighetti, Rosa Di Micco, Veronica Zuber, Marcella Pasetti, Nadia Di Muzio, Mariagrazia Rodighiero, Pietro Panizza, Isabella Sassi, Giovanna Petrella, Stefano Cascinu, Oreste Davide Gentilini, Giampaolo Bianchini

The Oncologist first published on June 23, 2020; doi: 10.1634/theoncologist.2020-0316


Fundamental Research in Oncology and Thrombosis 2 (FRONTLINE 2): A Follow‐Up Survey

Ajay K. Kakkar, Rupert Bauersachs, Anna Falanga, John Wong, Gloria Kayani, Alex Kahney, Rodney Hughes, Mark Levine

The Oncologist first published on May 08, 2020; doi: 10.1634/theoncologist.2019-0676


Molecular Guided Treatments in Gynecologic Oncology: Analysis of a Real‐World Precision Cancer Medicine Platform

Hossein Taghizadeh, Robert M. Mader, Leonhard Müllauer, Stefanie Aust, Stephan Polterauer, Heinz Kölbl, Veronika Seebacher, Christoph Grimm, Alexander Reinthaller, Gerald W. Prager

The Oncologist first published on May 05, 2020; doi: 10.1634/theoncologist.2019-0904


Neoadjuvant Chemotherapy Followed by Vaginal Radical Trachelectomy as Fertility‐Preserving Treatment for Patients with FIGO 2018 Stage 1B2 Cervical Cancer

Petra L.M. Zusterzeel, Johanna W.M. Aarts, Fraukje J.M. Pol, Petronella B. Ottevanger, Maaike A.P.C. van Ham

The Oncologist first published on April 27, 2020; doi: 10.1634/theoncologist.2019-0063


Antitumor Activity of Larotrectinib in Esophageal Carcinoma with NTRK Gene Amplification

Dirk Hempel, Thomas Wieland, Beate Solfrank, Vera Grossmann, Johanna Steinhard, Andrea Frick, Louisa Hempel, Thomas Eberl, Andreas Gaumann

The Oncologist first published on April 23, 2020; doi: 10.1634/theoncologist.2019-0641


How to Guarantee the Best of Care to Patients with Cancer During the COVID‐19 Epidemic: The Italian Experience

Giuseppe Curigliano

The Oncologist first published on April 16, 2020; doi: 10.1634/theoncologist.2020-0267


Renaissance of Radiotherapy in Intestinal Lymphoma? 10‐Year Efficacy and Tolerance in Multimodal Treatment of 134 Patients: Follow‐up of Two German Multicenter Consecutive Prospective Phase II Trials

Gabriele Reinartz, Caroline Molavi Tabrizi, Ruediger Liersch, Hansjoerg Ullerich, Dominik Hering, Kay Willborn, Juergen Schultze, Oliver Micke, Christian Ruebe, Wolfgang Fischbach, Martin Bentz, Severin Daum, Christiane Pott, Markus Tiemann, Peter Moeller, Andreas Neubauer, Martin Wilhelm, Georg Lenz, Wolfgang E. Berdel, Normann Willich, Hans T. Eich

The Oncologist first published on March 27, 2020; doi: 10.1634/theoncologist.2019-0783


Impact on Health‐Related Quality of Life of Parenteral Nutrition for Patients with Advanced Cancer Cachexia: Results from a Randomized Controlled Trial

Carole Bouleuc, Amélie Anota, Cécile Cornet, Ghislain Grodard, Antoine Thiery‐Vuillemin, Olivier Dubroeucq, Nathalie Crétineau, Véronique Frasie, Vincent Gamblin, Gisèle Chvetzoff, Laure Favier, Christophe Tournigand, Marie‐Christine Grach, Bruno Raynard, Sébastien Salas, Géraldine Capodano, Lionel Pazart, Régis Aubry

The Oncologist first published on March 25, 2020; doi: 10.1634/theoncologist.2019-0856


Immunotherapy in Underrepresented Populations of Patients with Cancer: Do We Have Enough Evidence at Present? A Focus on Patients with Major Viral Infections and Autoimmune Disorders

Andrea Antonuzzo, Fabio Calabrò, Pietro Quaglino, Fausto Roila, Gian Domenico Sebastiani, Francesco Spina, Giuseppe Pasqualetti, Diego Cortinovis, Enrico Tagliaferri, Alessandro Peri, Elena Margherita Presotto, Maria Francesca Egidi, Luca Giacomelli, Ferruccio Farroni, Massimo Di Maio, Emmanuele De Luca, Marco Danova, Florian Scottè, Karin Jordan, Paolo Bossi on behalf of Network Italiano Cure di Supporto in Oncologia (NICSO)

The Oncologist first published on March 17, 2020; doi: 10.1634/theoncologist.2020-0035


The European Medicines Agency Review of Gilteritinib (Xospata) for the Treatment of Adult Patients with Relapsed or Refractory Acute Myeloid Leukemia with an FLT3 Mutation

Kyriaki Tzogani, Hilde Røshol, Helga Haugom Olsen, Ida B. Aas, Marianne Løiten Dalhus, Gro Dahlseng Håkonsen, Laila Sortvik Nilssen, Vibeke Lindberg, Mats Økvist, Bjørg Bolstad, Irēna Rogovska, Natalja Karpova, Harald Enzmann, Christian Gisselbrecht, Francesco Pignatti

The Oncologist first published on March 10, 2020; doi: 10.1634/theoncologist.2019-0976


EMA Recommendation for the Pediatric Indications of Plerixafor (Mozobil) to Enhance Mobilization of Hematopoietic Stem Cells for Collection and Subsequent Autologous Transplantation in Children with Lymphoma or Malignant Solid Tumors

Dominik Karres Sahra Ali Paula B. van Hennik Sabine Straus Filip Josephson Geanne Thole Pieter J. Glerum Carla Herberts Negar Babae Ralf Herold Irene Papadouli Francesco Pignatti

The Oncologist first published on March 10, 2020; doi: 10.1634/theoncologist.2019-0898


It Is Time to Talk About Fertility and Immunotherapy

Narjust Duma, Matteo Lambertini

The Oncologist first published on February 24, 2020; doi: 10.1634/theoncologist.2019-0837


Sertoli Cell Tumors of the Testes: Systematic Literature Review and Meta‐Analysis of Outcomes in 435 Patients

Josias Grogg, Kym Schneider, Peter Karl Bode, Benedikt Kranzbühler, Daniel Eberli, Tullio Sulser, Anja Lorch, Joerg Beyer, Thomas Hermanns, Christian Daniel Fankhauser

The Oncologist first published on February 11, 2020; doi: 10.1634/theoncologist.2019-0692


Etiology and Prognosis of Pneumonia in Patients with Solid Tumors: A Prospective Cohort of Hospitalized Cases

Ana Fernández‐Cruz, Laura Ortega, Gonzalo García, Iria Gallego, Ana Álvarez‐Uría, Esther Chamorro‐de‐Vega, José Javier, García‐López, Ricardo González‐del‐Val, Pablo Martín‐Rabadán, Carmen Rodríguez, María Luisa Pedro‐Botet, Miguel Martín, Emilio Bouza

The Oncologist first published on February 11, 2020; doi: 10.1634/theoncologist.2019-0031


Challenges Conveying Clinical Equipoise and Exploring Patient Treatment Preferences in an Oncology Trial Comparing Active Monitoring with Radiotherapy (ROAM/EORTC 1308)

Frances C. Sherratt, Stephen L. Brown, Brian J. Haylock, Priya Francis, Helen Hickey, Carrol Gamble, Michael D. Jenkinson, Bridget Young

The Oncologist first published on February 11, 2020; doi: 10.1634/theoncologist.2019-0571


Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes

Fotios Loupakis, Ilaria Depetris, Paola Biason, Rossana Intini, Alessandra Anna Prete, Francesco Leone, Pasquale Lombardi, Roberto Filippi, Andrea Spallanzani, Stefano Cascinu, Luca Reggiani Bonetti, Giulia Maddalena, Nicola Valeri, Andrea Sottoriva, Luis Zapata, Roberta Salmaso, Giada Munari, Massimo Rugge, Angelo Paolo Dei Tos, Justin Golovato, John Z. Sanborn, Andrew Nguyen, Marta Schirripa, Vittorina Zagonel, Sara Lonardi, Matteo Fassan

The Oncologist first published on January 22, 2020; doi: 10.1634/theoncologist.2019-0611


The EORTC QLQ‐C30 Summary Score as a Prognostic Factor for Survival of Patients with Cancer: A Commentary

Bernd Kasper

The Oncologist first published on January 14, 2020; doi: 10.1634/theoncologist.2019-0749


Combined Expression of Plasma Thrombospondin‐2 and CA19‐9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach

Tessa Y.S. Le Large, Laura L. Meijer, Rosita Paleckyte, Lenka N.C. Boyd, Bart Kok, Thomas Wurdinger, Tim Schelfhorst, Sander R. Piersma, Thang V. Pham, Nicole C.T. van Grieken, Barbara M. Zonderhuis, Freek Daams, Hanneke W.M. van Laarhoven, Maarten F. Bijlsma, Connie R. Jimenez, Elisa Giovannetti, Geert Kazemier

The Oncologist first published on January 14, 2020; doi: 10.1634/theoncologist.2019-0680


Predictive Impact of Mucinous Tumors on the Clinical Outcome in Patients with Poorly Differentiated, Stage II Colon Cancer: A TOSCA Subgroup Analysis

Gerardo Rosati Fabio Galli Maurizio Cantore Francesca Bergamo Maria Banzi Maria Giulia Zampino Rodolfo Mattioli Giovanni Gerardo Cardellino Monica Ronzoni Maria Di Bartolomeo Stefano Tamberi Paolo Marchetti Lorenza Rimassa Domenico Corsi Anna Maria Bochicchio Fabrizio Artioli Roberto Labianca Francesca Galli Eliana Rulli Domenico Bilancia Giacomo Bregni on behalf of TOSCA (Three or Six Colon Adjuvant) Investigators

The Oncologist first published on January 13, 2020; doi: 10.1634/theoncologist.2019-0736


Managing Hyperprogressive Disease in the Era of Programmed Cell Death Protein 1/Programmed Death‐Ligand 1 Blockade: A Case Discussion and Review of the Literature

Miruna Grecea, Aurélien Marabelle, Samy Ammari, Christophe Massard, Stéphane Champiat

The Oncologist first published on December 24, 2019; doi: 10.1634/theoncologist.2019-0671


Real‐World Evidence in Oncology: Opportunities and Limitations

Massimo Di Maio, Francesco Perrone, Pierfranco Conte

The Oncologist first published on December 24, 2019; doi: 10.1634/theoncologist.2019-0647


Single‐Center Experience with Ifosfamide Monotherapy as Second‐Line Treatment of Recurrent/Metastatic Osteosarcoma

Arie Jan Verschoor, Frank M. Speetjens, P.D. Sander Dijkstra, Marta Fiocco, Michiel A.J. van de Sande, Judith V.M.G. Bovée, Hans Gelderblom

The Oncologist first published on December 19, 2019; doi: 10.1634/theoncologist.2019-0528


Blinatumomab for Acute Lymphoblastic Leukemia: The First Bispecific T‐Cell Engager Antibody to Be Approved by the EMA for Minimal Residual Disease

Sahra Ali, Alexandre Moreau, Daniela Melchiorri, Jorge Camarero, Filip Josephson, Odoardo Olimpier, Jonas Bergh, Dominik Karres, Kyriaki Tzogani, Christian Gisselbrecht, Francesco Pignatti

The Oncologist first published on November 14, 2019; doi: 10.1634/theoncologist.2019-0559


The EORTC QLQ‐C30 Summary Score as Prognostic Factor for Survival of Patients with Cancer in the “Real‐World”: Results from the Population‐Based PROFILES Registry

Olga Husson, Belle H. de Rooij, Jacobien Kieffer, Simone Oerlemans, Floortje Mols, Neil K. Aaronson, Winette T.A. van der Graaf, Lonneke V. van de Poll‐Franse

The Oncologist first published on October 31, 2019; doi: 10.1634/theoncologist.2019-0348


CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF‐MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement

Matteo Claudio Da Vià, Antonio Giovanni Solimando, Andoni Garitano‐Trojaola, Santiago Barrio, Umair Munawar, Susanne Strifler, Larissa Haertle, Nadine Rhodes, Eva Teufel, Cornelia Vogt, Constantin Lapa, Andreas Beilhack, Leo Rasche, Hermann Einsele, K. Martin Kortüm

The Oncologist first published on October 18, 2019; doi: 10.1634/theoncologist.2019-0356


The European Medicines Agency Review of Kymriah (Tisagenlecleucel) for the Treatment of Acute Lymphoblastic Leukemia and Diffuse Large B‐Cell Lymphoma

Sahra Ali, Rune Kjeken, Christiane Niederlaender, Greg Markey, Therese S. Saunders, Mona Opsata, Kristine Moltu, Bjørn Bremnes, Eirik Grønevik, Martine Muusse, Gro D. Håkonsen, Venke Skibeli, Maria Elisabeth Kalland, Ingrid Wang, Ingebjørg Buajordet, Ania Urbaniak, John Johnston, Khadija Rantell, Essam Kerwash, Martina Schuessler‐Lenz, Tomas Salmonson, Jonas Bergh, Christian Gisselbrecht, Kyriaki Tzogani, Irene Papadouli, Francesco Pignatti

The Oncologist first published on October 16, 2019; doi: 10.1634/theoncologist.2019-0233


Guillain‐Barré Syndrome During Platinum‐Based Chemotherapy: A Case Series and Review of the Literature

Evangelia Pappa, Giulia Berzero, Bastien Herlin, Damien Ricard, Camille Tafani, Perrine Devic, Denis Maillet, Alaina Borden, Karine Viala, Thierry Maisonobe, Timothée Lenglet, Nicolas Weiss, Dimitri Psimaras

The Oncologist first published on October 15, 2019; doi: 10.1634/theoncologist.2019-0255


A Large, Multicenter, Retrospective Study on Efficacy and Safety of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Ovarian Cancer (MITO RT1 Study): A Collaboration of MITO, AIRO GYN, and MaNGO Groups

Gabriella Macchia, Roberta Lazzari, Nicoletta Colombo, Concetta Laliscia, Giovanni Capelli, Giuseppe Roberto D'Agostino, Francesco Deodato, Ernesto Maranzano, Edy Ippolito, Sara Ronchi, Fabiola Paiar, Marta Scorsetti, Savino Cilla, Rossana Ingargiola, Alessandra Huscher, Anna Maria Cerrotta, Andrei Fodor, Lisa Vicenzi, Donatella Russo, Simona Borghesi, Elisabetta Perrucci, Sandro Pignata, Cynthia Aristei, Alessio Giuseppe Morganti, Giovanni Scambia, Vincenzo Valentini, Barbara Alicja Jereczek‐Fossa, Gabriella Ferrandina

The Oncologist first published on October 2, 2019; doi: 10.1634/theoncologist.2019-0328


Real‐World Delivery of Rucaparib to Patients with Ovarian Cancer: Recommendations Based on an Integrated Safety Analysis of ARIEL2 and Study 10

Yvette Drew, Rebecca S. Kristeleit, Ana Oaknin, Isabelle Ray‐Coquard, Noor Md. Haris, Elizabeth M. Swisher

The Oncologist first published on October 1, 2019; doi: 10.1634/theoncologist.2019-0229


Impact of Older Age and Comorbidity on Locoregional and Distant Breast Cancer Recurrence: A Large Population‐Based Study

Anna Z. de Boer, Heleen C. van der Hulst, Nienke A. de Glas, Perla J. Marang‐van de Mheen, Sabine Siesling, Linda de Munck, Kelly M. de Ligt, Johanneke E. A. Portielje, Esther Bastiaannet, Gerrit Jan Liefers

The Oncologist first published on September 12, 2019; doi: 10.1634/theoncologist.2019-0412


Premature Termination of a Randomized Controlled Trial on Image‐Guided Stereotactic Body Radiotherapy of Metastatic Spinal Cord Compression

Morten Hiul Suppli, Per Munck af Rosenschold, Benny Dahl, Anne Kiil Berthelsen, Svend Aage Engelholm, Helle Pappot

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0672


The McCAVE Trial: Vanucizumab plus mFOLFOX‐6 Versus Bevacizumab plus mFOLFOX‐6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC)

Johanna C. Bendell, Tamara Sauri, Antonio Cubillo Gracián, Rafael Alvarez, Carlos López‐López, Pilar García‐Alfonso, Maen Hussein, Maria‐Luisa Limon Miron, Andrés Cervantes, Clara Montagut, Cristina Santos Vivas, Alberto Bessudo. Patricia Plezia Veerle Moons, Johannes Andel, Jaafar Bennouna, Andre van der Westhuizen, Leslie Samuel, Simona Rossomanno, Christophe Boetsch, Angelika Lahr, Izolda Franjkovic, Florian Heil, Katharina Lechner, Oliver Krieter, Herbert Hurwitz, for the McCAVE Study Group

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0291


Biliary Stone Disease in Patients with Neuroendocrine Tumors Treated with Somatostatin Analogs: A Multicenter Study

Nicole Brighi, Francesco Panzuto, Roberta Modica, Fabio Gelsomino, Manuela Albertelli, Sara Pusceddu, Sara Massironi, Giuseppe Lamberti, Maria Rinzivillo, Antongiulio Faggiano, Andrea Spallanzani, Diego Ferone, Natalie Prinzi, Roberta Elisa Rossi, Bruno Annibale, Anna Maria Colao, Davide Campana

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0403


Prognostic and Predictive Value of Microsatellite Instability, Inflammatory Reaction and PD‐L1 in Gastric Cancer Patients Treated with Either Adjuvant 5‐FU/LV or Sequential FOLFIRI Followed by Cisplatin and Docetaxel: A Translational Analysis from the ITACA‐S Trial

Maria Di Bartolomeo, Federica Morano, Alessandra Raimondi, Rosalba Miceli, Salvatore Corallo, Elena Tamborini, Federica Perrone, Maria Antista, Monica Niger, Alessandro Pellegrinelli, Giovanni Randon, Filippo Pagani, Antonia Martinetti, Giovanni Fucà, Filippo Pietrantonio on behalf of ITACA‐S study group

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0471


Olanzapine Versus Haloperidol for Treatment of Delirium in Patients with Advanced Cancer: A Phase III Randomized Clinical Trial

Maurice J.D.L. van der Vorst, Elisabeth C.W. Neefjes, Manon S.A. Boddaert, Bea A.T.T. Verdegaal, Aart Beeker, Saskia C.C. Teunissen, Aartjan T.F. Beekman, Janneke A. Wilschut, Johannes Berkhof, Wouter W.A. Zuurmond, Henk M.W. Verheul

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0470


Implementation of Best Practice Recommendations for Palliative Care in German Comprehensive Cancer Centers

Susanne Gahr, Sarah Lödel, Julia Berendt, Michael Thomas, Christoph Ostgathe

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0126


Effect of a Skills Training for Oncologists and a Patient Communication Aid on Shared Decision Making About Palliative Systemic Treatment: A Randomized Clinical Trial

Inge Henselmans, Hanneke W.M. van Laarhoven, Pomme van Maarschalkerweerd, Hanneke C.J.M. de Haes, Marcel G.W. Dijkgraaf, Dirkje W. Sommeijer, Petronella B. Ottevanger, Helle‐Brit Fiebrich, Serge Dohmen, Geert‐Jan Creemers, Filip Y.F.L. de Vos, Ellen M.A. Smets

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0453


Access to Novel Drugs for Non‐Small Cell Lung Cancer in Central and Southeastern Europe: A Central European Cooperative Oncology Group Analysis

Tanja Cufer Tudor E. Ciuleanu Peter Berzinec Gabriela Galffy Marko Jakopovic Jacek Jassem Dragana Jovanovic Zhasmina Mihaylova Gyula Ostoros Christiane Thallinger Milada Zemanova Christoph Zielinski

The Oncologist first published on September 10, 2019; doi: 10.1634/theoncologist.2019-0523


The Oncology Data Network (ODN): A Collaborative European Data‐Sharing Platform to Inform Cancer Care

David Kerr, Dirk Arnold, Jean‐Yves Blay, Christian Buske, Alfredo Carrato, Winald Gerritsen, Marc Peters

The Oncologist first published on September 5, 2019; doi: 10.1634/theoncologist.2019-0337


Lifetime Transfusion Burden and Transfusion‐Related Iron Overload in Adult Survivors of Solid Malignancies

F.J. Sherida H. Woei‐A‐Jin, Shu Zhen Zheng, Inci Kiliçsoy, Francisca Hudig, Saskia A.C. Luelmo, Judith R. Kroep, Hildo J. Lamb, Susanne Osanto

The Oncologist first published on August 27, 2019; doi: 10.1634/theoncologist.2019-0222


Programmed Cell Death Ligand 1 in Breast Cancer: Technical Aspects, Prognostic Implications, and Predictive Value

Federica Miglietta, Gaia Griguolo, Valentina Guarneri, Maria Vittoria Dieci

The Oncologist first published on August 23, 2019; doi:10.1634/theoncologist.2019-0197


Effects of Exercise on Chemotherapy Completion and Hospitalization Rates: The OptiTrain Breast Cancer Trial

Sara Mijwel, Kate A. Bolam, Jacob Gerrevall, Theodoros Foukakis, Yvonne Wengström, Helene Rundqvist

The Oncologist first published on August 7, 2019; doi: 10.1634/theoncologist.2019-0262


Predicting Chemotherapy Toxicity and Death in Older Adults with Colon Cancer: Results of MOST Study

Frédérique Retornaz, Olivier Guillem, Frédérique Rousseau, Francois Morvan, Yves Rinaldi, Sophie Nahon, Chantal Castagna, Rabia Boulahssass, Michel Grino, Dany Gholam

The Oncologist first published on August 6, 2019; doi: 10.1634/theoncologist.2019-0241


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